Effect of Storage Time and Temperature 
on Vitamin Levels of Tablets

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LabDiet® Monkey MV 5073 was stored for seven weeks at 72°F (22°C), then one lot was stored for an additional fifty-three weeks at 72° F and another lot was stored for an additional fifty-three weeks at 90° F. Vitamin assays were performed at 7, 34, and 60 weeks of storage.

 

Vitamin A*

Vitamin C

Riboflavin

Niacin

 

IU/tablet

mg/tablet

mg/tablet

mg/tablet

Specifications

2000

60

1.70

20.0

7 weeks at 72° F (22°C)

2510

67

1.62

18.1

34 weeks at 72° F (22°C)

2260

68

1.74

21.2

60 weeks at 72° F (22°C)

2130

64

1.74

19.1

7 weeks at 72° F followed by 27 weeks at 90°F (32°C)

1680

65

1.68

18.7

7 weeks at 72° F followed by 53 weeks at 90°F (32°C)

1380

62

1.74

19.9

* Diet formulated to contain 3000 IU/tablet at time of manufacture.

As the data indicate, LabDiet® Monkey MV 5073 has a shelf life of up to one year if stored at room temperature (72°F or 22°C). The levels of vitamin C, riboflavin, and niacin remain relatively consistent throughout the storage period. While it may appear that the levels increase over a period, this result is due to analytical variability.

The level of vitamin A decreased as storage time increased, and decreased below specifications if the tablet were stored at 90°F.

These results are typical of what may be expected with all of the LabDiet® tablets. Storage of any LabDiet® product at 90°F is never recommended and data on storage at that temperature is included to demonstrate that the stability of tablets, and in particular vitamin A, decreases as storage temperature increases.

Storage Requirements of PMI® Nutrition International Test Diets

PMI® Nutrition International Purified Test Diets contain no preservatives, therefore they require special precautions to preserve their nutritional quality.

Most Purified Test Diets should be refrigerated or frozen when not being fed. For short-term studies, usually refrigeration (2°C) in a dry location is adequate. For long-term studies, the diets should always be frozen (-20°C).

The unique nature of the Custom and Modified Diets necessitates individualized storage requirements. Most of the custom and modified diets can be stored in a manner similar to their LabDiet® counterparts. Some diets, like high fat diets, require refrigeration or freezing.

For questions about the storage requirements of your Purified Test Diet, Custom Diet, or Modified Diet, contact the PMI® Nutrition International Test Diet Unit.

PMI® Nutrition International Test Diets
505 North 4th
Richmond, IN 47374
(765) 966 1885
Fax: (765) 935 0241
www.testdiet.com