A LOOK AT THE BIG PICTURE;
Isoflavones, the most common form of phytoestrogens, are detectable in most all diets fed to laboratory animals. Isoflavones are not bad for animals; however more and more researchers need to verify the levels contained in the diets for specific study area. Before making your decision about isoflavones, there is more that you should know. FACTS ON ISOFLAVONES IN DIETS
- Isoflavones (IF) are a common class of phytoestrogens. They are plant-derived compounds capable of estrogenic or antiestrogenic effects on the animals consuming them. Isoflavones are structural mimics of endogenous 17ß-estradiol (Seielstad, et al., 1995).
- IFs are nothing new. As early as the 1920s, IFs were found to affect body metabolism and in the 1940s, IFs found in red clover were found to affect sheep fertility.
- Since the early 1990s, with an increase in endocrine disruptor (ED) awareness, IFs have been identified as contributing factors that may affect the outcome of such studies.
- In the lab community, some advocate feeding low IF diets to all of their animals. However, others feel the low IF diets should only be used where appropriate.
Click the link below to find information to assist you in making the correct choice for your lab animals. The Facts about Isoflavones: A Look at the Big Picture