Advanced Protocol™ Verified PicoLab® Rodent IF Diet is a Constant Nutrition™, 20 % protein diet formulated for rat and mouse colonies where dietary estrogenic activity needs to be assured. Irradiation treatment and special 4-ply packaging provide virtually bacteria-free dietary control. It is especially suited for animals maintained in barrier facilities. To be fed free choice.
| Features and Benefits |
Formulated with 20% protein |
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Verified to contain less than 50 ppm total isoflavones (genistein, daidzein and
glycitein) |
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Reliable microbial control |
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Precision processing assures Constant Nutrition™ quality |
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Irradiation eliminates the need for autoclaving |
Product Forms Available |
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Oval pellets, 10 mm x 16 mm x 25 mm length (3/8”x5/8”x1”) |
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Meal (ground pellets), special order |
Strains not requiring high fat diets should be fed 5V02, while those showing optimum reproductive performance when fed high fat diets should receive Advanced Protocol™ Verified PicoLab® Advanced Protocol™ Verified PicoLab® Mouse 50 IF Diet is a Constant Nutrition™ formulation providing 20% protein for mouse colonies that require extra levels of energy and where dietary estrogenic activity needs to be assured. Irradiation treatment and special 4-ply packaging provide virtually bacteria-free dietary control. Especially suited for transgenic mice and breeding mice colonies maintained in barrier facilities. Mouse 50 IF Diet - 5V03 when involved in protocols involving estrogen-sensitive parameters.
An estrogen-sensitive parameter in the growing, ovariectomized mouse is the uterus. A smaller uterus indicates less estrogenic activity in the diet. When compared on a basis relative to body weight (BW), less than 50 ppm total isoflavones produced a uterus that was 15% smaller than a uterus produced by approximately 400 ppm total isoflavones.
Outbred (Sprague-Dawley) rats had equal reproductive performance (pups at birth and weaning) comparing 5V02 and 5001.
Inbred (Fischer-344) rats fed 5V02 produced less pups at birth and weaning compared to rats fed 5001.
G U A R A N T E E D A N A L Y S I S |
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| Crude protein not less than | 20.0% |
| Crude fat not less than | 4.5% |
| Crude fiber not more than | 6.0% |
I N G R E D I E N T S
Ground corn, ground wheat, wheat middlings, corn gluten meal, ground oats, casein, corn oil, calcium carbonate, brewers dried yeast, potassium carbonate, dicalcium phosphate, salt, L-lysine, menadione sodium bisulfite (source of vitamin K), choline chloride, magnesium oxide, pyridoxine hydrochloride, DL-methionine, L-tryptophan, vitamin A acetate, cholecalciferol (source of vitamin
D3), ferrous sulfate, dl-alpha tocopheryl acetate (source of vitamin E), thiamin mononitrate, folic acid, calcium pantothenate, nicotinic acid, riboflavin, cyanocobalamin (source of vitamin
B12), manganese oxide, zinc oxide, ferrous carbonate, copper sulfate, zinc sulfate, calcium iodate, cobalt carbonate, sodium selenite.
F E E D I N G D I R E C T I O N S
Feed ad libitum. Plenty of fresh, clean water should be available to the animals at all times.
Rats- All rats will eat varying amounts of feed depending on their genetic origin. Larger strains will eat between 15-30 grams per day. Smaller strains will eat between 12-15 grams per day. Feeders in rat cages should be designed to hold two to three days supply of feed at one time.
Mice-Adult mice will eat 4 to 5 grams of pelleted ration daily. Some of the larger strains may eat as much as 8 grams per day per animal. Feed should be available on a free choice basis in wire feeders above the floor of the cage.
Hamsters-Adults will eat 10 to 14 grams per day.
| C H E M I C A L C O M P O S I T I O N | |
| Nutrients (2) | |
| Protein, % |
20.0 |
| Arginine, % | 0.81 |
| Cystine, % | 0.27 |
| Glycine, % | 0.62 |
| Histidine, % | 0.47 |
| Isoleucine, % | 0.95 |
| Leucine, % | 2.19 |
| Lysine, % | 1.15 |
| Methionine, % | 0.51 |
| Phenylalanine, % | 1.05 |
| Tyrosine, % | 0.79 |
| Threonine, % | 0.70 |
| Tryptophan, % | 0.24 |
| Valine, % | 1.07 |
| Serine, % | 1.00 |
| Aspartic Acid, % | 1.41 |
| Glutamic Acid, % | 4.96 |
| Alanine, % | 1.21 |
| Proline, % | 1.99 |
| Taurine, % | 0.00 |
| Fat (ether extract), % | 4.5 |
| Fat (acid hydrolysis), % | 5.7 |
| Cholesterol, ppm | 0.00 |
| Linoleic Acid, % | 2.69 |
| Linolenic Acid, % | 0.10 |
| Arachidonic Acid, % | 0.00 |
| Omega-3 Fatty Acids, % | 0.10 |
| Total Saturated Fatty Acids, % | 0.83 |
| Total
Monounsaturated Fatty Acids, % |
1.19 |
| Fiber (Crude), % | 3.9 |
| Neutral Detergent Fiber3, % | 16.2 |
| Acid Detergent Fiber4, % | 5.3 |
| Nitrogen-Free Extract (by difference), % |
57.1 |
| Starch, % |
40.2 |
| Glucose, % |
0.19 |
| Fructose, % |
0.19 |
| Sucrose, % |
0.39 |
| Lactose, % |
0.01 |
| Total Digestible Nutrients, % |
75.8 |
| Gross Energy, kcal/gm |
4.07 |
| Physiological
Fuel Value5, kcal/gm |
3.49 |
| Metabolizable Energy, kcal/gm |
3.20 |
| Minerals | |
| Ash, % |
4.5 |
| Calcium, % |
0.79 |
| Phosphorus, % |
0.54 |
| Phosphorus (non-phytate), % |
0.29 |
| Potassium, % |
0.80 |
| Magnesium, % |
0.20 |
| Sulfur, % |
0.17 |
| Sodium, % |
0.23 |
| Chlorine, % |
0.50 |
| Fluorine, ppm |
4.4 |
| Iron, ppm |
200 |
| Zinc, ppm |
120 |
| Manganese, ppm |
130 |
| Copper, ppm |
15 |
| Cobalt, ppm |
0.45 |
| Iodine, ppm |
1.49 |
| Chromium, ppm |
0.34 |
| Selenium, ppm |
0.20 |
| Vitamins | |
| Carotene, ppm |
1.6 |
| Vitamin K (as menadione), ppm |
7.1 |
| Thiamin Hydrochloride, ppm |
19 |
| Riboflavin, ppm |
9.1 |
| Niacin, ppm |
120 |
| Pantothenic Acid, ppm |
22 |
| Choline Chloride, ppm |
1800 |
| Folic Acid, ppm |
2.7 |
| Pyridoxine, ppm |
11 |
| Biotin, ppm |
0.14 |
| B12, mcg/kg |
26 |
| Vitamin A, IU/gm |
26 |
| Vitamin D3 (added), IU/gm |
2.0 |
| Vitamin E, IU/kg |
100 |
| Ascorbic Acid, mg/gm |
-- |
| Calories provided by: | |
| Protein, % | 22.929 |
| Fat (ether extract), % | 11.608 |
| Carbohydrates, % | 65.463 |
* Product Code
1. Based on the latest ingredient analysis information. Since nutrient composition
of natural ingredients varies, analysis will differ accordingly.
2. Nutrients expressed as percent of ration except where otherwise indicated.
3. NDF = approximately cellulose, hemi-cellulose and lignin.
4. ADF = approximately cellulose and lignin.
5. Physiological Fuel Value (kcal/gm) = Sum of decimal fractions of protein, fat and
carbohydrate (use Nitrogen Free Extract) x 4,9,4 kcal/gm respectively.
02/17/03